PQQ (Pyrroloquinoline Quinone)

Cofactor that stimulates mitochondrial biogenesis — the growth of new mitochondria

PQQ is a redox cofactor found in trace amounts in foods like natto, green tea, and parsley. Its primary mechanism of interest in longevity is its ability to activate PGC-1α, the master regulator of mitochondrial biogenesis — the process by which cells grow new mitochondria. This makes it a complement to CoQ10, which supports existing mitochondria.